Question
The following pedigree chart shows the inheritance of a genetic disorder up to three generations of a family. Observe the chart and answer the questions that follow.
(i) Is the disease sex-linked or autosomal as per the chart ? Give reasons in support of your answer.
(ii) Is it a recessive or a dominant disorder?
(iii) Write the genotypes of the individuals 'C', 'D' and 'H'.
(iv)a) If the female 'D' marries a normal man, what will be the probability of their daughter being a sufferer of this disease ?
or
b) If the mother 'B' is a carrier of the disease, what will be the probability of their daughter being a sufferer of this disease ?
Answer :
(i)
• Sex linked disorder
• More males are affected in the family as males have only one X chromosome which if affected expresses
(ii) Recessive disorder
(iii) C -XXᶜ; D- XXᶜ; H- XXᶜ‘c’ is affected allele, accept other symbols used for the same
(iv)
a) Probability 0%
or
b) Probability-50%
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